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13 January 2012 18:59:12 GMT
Dear Dr. Holmes,
With reference to the above publication, I will appreciate your responses to the following questions.
On what bases were the twenty-three patients recruited from the clinic population?
Are there clinical data comparing the the patients who were recruited with the patients who were not recruited?
How was the medication being taken by the patients managed during the course of the study?
To what degree was the research team involved in any changes in medication during the course of the study?
To what degree did the research team liaise with the Key Worker?
Are there clinical data that show what happened to the patients during the course of the study, in terms of, for example, Life Events, General Practitioner appointments, Key Worker appointments, clinic appointments, hospital admissions, suicidal behaviour and anti-social behaviour?
To what degree was the effect of medication construed as a factor in the time-series processes?
To what degree was the effect of changes of medication construed as a factor in the time-series processes?
To what degree were social variables assessed as potentially independent factors in the time-series processes?
Michael Robinson MD.
26 January 2012 11:44:25 GMT
thank you for your email which I have picked up after being out of the office.
I only wish that I had more time to enter into correspondence, but I am afraid that the pressure of clinical and university work means that I am unable to answer detailed questions to all email requests at the present time.
Only the variables analysed are reported in the paper, therefore I am unable to provide data on medication, key working, social variables, clinical variable etc. - treatment was as usual. These would be interesting factors to study in the future
thank you for your interest in this work
Recourse to the National Research Ethics Service resulted in a formal enquiry, and a published correction.